Mayim Bialik as Amy Fowler
Who wouldn’t know the incredibly intelligent Amy Farah Fowler, who is the partner of Cooper in the famous series? Fowler plays an important role on how Cooper slowly developed from being aloof and socially inept to be her love interest towards the end. Mayim Bialik is probably as smart, or even smarter than her character. Just like in The Big Bang Theory, Bialik has a B.S. degree in neuroscience, minors in Hebrew and Jewish studies, and also a Ph.D. in neuroscience.
Mayim Bialik As Amy Fowler
Simon Helberg as Howard Wolowitz
Now among the four main male characters in the series, meet Howard Wolowitz who plays an engineer and astronaut who had a very overbearing mother. Being the only one without a Ph.D, Wolowitz has always been left behind by the other three. Eventually, he gets hitched to Bernadette, Penny’s coworker in the restaurant. The 36-year old was also nominated for a Golden Globe for the 2016 film Florence Foster Jenkins. Aside from being an actor, Helberg works as a musician and comedian.
Simon Helberg As Howard Wolowitz
