Laurie Metcalf as Mary Cooper
Metcalf plays Mary Cooper, Sheldon’s mother, who is a devout born-again Christian from East Texas. Her character has been a good contradiction to Sheldon’s strong persona. Their polar opposite relationship in the series has gained many fans. In 1988, Laurie Metcalf snagged the famous role of Jackie Harris on Roseanne, which sky-rocketed her career. The 62-year old actress who considers herself as a workaholic has numerous accolades and nominations to her name.
Laurie Metcalf As Mary Cooper
Sara Gilbert as Leslie Winkle
Another Roseanne mainstay alongside Galecki, is Sara Gilbert who played Leslie Winkle, an experimental physicist who works in the same laboratory with Leonard. Her cold and sarcastic character worked well with Hofstadter’s sensitive character. Sara Gilbert has made many appearances on shows such as 24, Will & Grace, and Private Practice. Aside from acting, she’s also a co-host and executive producer of The Talk.
Sara Gilbert As Leslie Winkle
